The correlation between sampling site and gene expression in the term human placenta
SM Wyatt, FT Kraus, CR Roh, U Elchalal, DM Nelson… - Placenta, 2005 - Elsevier
Using oligonucleotide microarrays we recently identified a set of transcripts that were up-
regulated in hypoxic human trophoblasts. To test the hypothesis that expression of hypoxia-
related placental transcripts depends on sampling site we analyzed nine different sites from
term human placentas (n= 6), obtained after uncomplicated pregnancies. These sites
spanned the placental center to the lateral border and the basal to the chorionic plate.
Relative gene expression at each site, determined using quantitative PCR, was correlated …
regulated in hypoxic human trophoblasts. To test the hypothesis that expression of hypoxia-
related placental transcripts depends on sampling site we analyzed nine different sites from
term human placentas (n= 6), obtained after uncomplicated pregnancies. These sites
spanned the placental center to the lateral border and the basal to the chorionic plate.
Relative gene expression at each site, determined using quantitative PCR, was correlated …
